Basic Information
ID: ALA4051488
Type: Binding
Description: Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NAD(+) by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4051488
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.59 | 4.61 | 4.61 |
| 414.58 | 4.97 | 4.97 |
| 428.60 | 5.85 | 5.85 |
| 473.65 | 4.95 | 4.95 |
| 412.61 | 6.18 | 6.18 |
| 440.66 | 6.96 | 6.96 |
| 471.63 | 5.36 | 5.36 |
| 443.62 | 5.07 | 5.07 |
| 433.58 | 3.46 | 3.46 |
| 392.55 | 5.93 | 5.93 |
| 399.59 | 5.26 | 5.26 |
| 414.58 | 4.97 | 4.97 |
| 370.52 | 5.01 | 5.01 |
| 407.56 | 5.52 | 5.52 |
| 514.70 | 5.82 | 5.82 |
| 393.54 | 5.41 | 5.41 |
| 412.61 | 6.18 | 6.18 |
| 431.61 | 4.62 | 4.62 |
| 413.59 | 5.58 | 5.58 |
| 457.60 | 5.27 | 5.27 |
| 322.48 | 4.33 | 4.33 |
| 420.61 | 5.03 | 5.03 |
| 336.51 | 4.51 | 4.51 |
| 426.63 | 6.57 | 6.57 |
| 443.62 | 5.07 | 5.07 |
| 410.57 | 4.85 | 4.85 |
| 447.61 | 3.86 | 3.86 |
| 447.61 | 4.28 | 4.28 |
| 457.65 | 5.19 | 5.19 |
| 393.56 | 3.83 | 3.83 |
| 394.54 | 4.30 | 4.30 |
| 305.43 | 3.59 | 3.59 |
| 411.56 | 4.25 | 4.25 |
| 484.67 | 5.21 | 5.21 |
| 352.44 | 4.97 | 4.97 |
| 416.57 | 5.74 | 5.74 |
| 459.67 | 5.43 | 5.43 |
| 433.02 | 6.01 | 6.01 |
| 452.03 | 4.96 | 4.96 |
| 513.71 | 5.40 | 5.40 |
| 457.65 | 5.11 | 5.11 |
| 484.67 | 5.28 | 5.28 |
| 442.64 | 5.04 | 5.04 |
| 398.58 | 5.79 | 5.79 |
| 413.59 | 5.58 | 5.58 |
| 396.61 | 7.17 | 7.17 |
| 428.60 | 5.42 | 5.42 |
| 412.61 | 6.18 | 6.18 |
| 471.63 | 5.36 | 5.36 |
| 445.64 | 4.93 | 4.93 |
| 431.61 | 4.62 | 4.62 |
| 398.51 | 4.50 | 4.50 |
| 417.59 | 4.31 | 4.31 |
| 528.73 | 5.18 | 5.18 |
| 500.67 | 4.30 | 4.30 |
| 392.55 | 6.65 | 6.65 |
| 366.49 | 3.82 | 3.82 |
| 397.53 | 5.11 | 5.11 |
| 337.50 | 3.83 | 3.83 |
| 484.67 | 5.28 | 5.28 |
| 398.58 | 5.79 | 5.79 |
| 414.58 | 4.76 | 4.76 |
| 339.49 | 2.54 | 2.54 |
| 471.67 | 5.80 | 5.80 |
| 240.35 | 2.40 | 2.40 |
| 380.49 | 5.45 | 5.45 |
| 520.73 | 4.63 | 4.63 |
| 423.59 | 5.69 | 5.69 |