Basic Information
ID: ALA4051539
Type: Binding
Description: Inhibition of Halo-tagged histone H4 binding to C-terminally NanoLuc luciferase conjugated human BRPF2 BD (560 to 666 residues) expressed in human HCT116 cells after 4 to 24 hrs by BRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Bromodomain-containing protein 1(ALA2176774)
Document: ALA4049437
Inhibition of Halo-tagged histone H4 binding to C-terminally NanoLuc luciferase conjugated human BRPF2 BD (560 to 666 residues) expressed in human HCT116 cells after 4 to 24 hrs by BRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4051539
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.50 | 3.74 | 3.74 |
| 526.64 | 2.82 | 2.82 |
| 470.53 | 3.10 | 3.10 |
| 401.42 | 2.75 | 2.75 |
| 456.50 | 2.98 | 2.98 |
| 469.55 | 2.89 | 2.89 |
| 405.84 | 3.79 | 3.79 |
| 509.61 | 3.67 | 3.67 |
| 387.40 | 2.84 | 2.84 |
| 429.48 | 3.06 | 3.06 |
| 497.60 | 3.67 | 3.67 |
| 454.53 | 4.13 | 4.13 |
| 371.40 | 3.14 | 3.14 |
| 484.56 | 3.75 | 3.75 |