Basic Information
ID: ALA4051638
Type: Binding
Description: Inhibition of human BRD4 BD1 (67 to 152 residues) up to 20 uM preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylated histone H4 (1 to 20 residues) peptide as substrate measured after 1 hr by TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4049437
Inhibition of human BRD4 BD1 (67 to 152 residues) up to 20 uM preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylated histone H4 (1 to 20 residues) peptide as substrate measured after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4051638
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.37 | 2.83 | 2.83 |