Basic Information
ID: ALA4051946
Type: Functional
Description: Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4051946
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.54 | 7.25 | 7.25 |
| 640.71 | 6.02 | 6.02 |
| 455.51 | 6.36 | 6.36 |
| 499.56 | 6.24 | 6.24 |
| 644.76 | 7.40 | 7.40 |
| 503.52 | 6.51 | 6.51 |
| 571.62 | 6.47 | 6.47 |
| 489.95 | 7.01 | 7.01 |
| 472.49 | 5.74 | 5.74 |
| 467.54 | 6.23 | 6.23 |
| 699.80 | 6.28 | 6.28 |
| 499.56 | 6.68 | 6.68 |
| 511.57 | 6.92 | 6.92 |
| 477.61 | 6.71 | 6.71 |
| 404.42 | 4.38 | 4.38 |
| 485.53 | 6.37 | 6.37 |
| 449.55 | 6.09 | 6.09 |
| 497.57 | 6.24 | 6.24 |
| 708.59 | 6.42 | 6.42 |
| 808.92 | 5.21 | 5.21 |
| 494.37 | 7.66 | 7.66 |
| 519.98 | 7.02 | 7.02 |
| 557.59 | 6.38 | 6.38 |
| 455.51 | 6.36 | 6.36 |
| 471.50 | 5.58 | 5.58 |
| 515.56 | 6.38 | 6.38 |
| 626.70 | 6.42 | 6.42 |
| 556.65 | 6.65 | 6.65 |
| 486.52 | 5.76 | 5.76 |
| 566.65 | 6.28 | 6.28 |
| 467.54 | 6.23 | 6.23 |
| 499.51 | 5.85 | 5.85 |