Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation up to 10 uM after overnight incubation by luciferase reporter...

Basic Information

ID: ALA4051992

Type: Functional

Description: Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation up to 10 uM after overnight incubation by luciferase reporter gene assay relative to lithocholic acid

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  G-protein coupled bile acid receptor 1(ALA5409)

Document:  ALA4049444

Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation up to 10 uM after overnight incubation by luciferase reporter gene assay relative to lithocholic acid: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
557.596.386.38
499.515.855.85