Assay Report Card

Basic Information

ID: ALA4052013

Type: Binding

Description: Inhibition of Influenza A virus A/Udorn307/72 H3N2 amantadine-resistant M2 proton channel V27A mutant expressed in Xenopus laevis oocytes assessed as dissociation rate constant at pH 5.5 incubated for 2 mins followed by compound washout at -20 mV holding potential by two-electrode voltage clamp assay

Organism: Influenza A virus (A/Udorn/307/1972(H3N2))

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
151.251.911.91
219.373.343.34
261.412.812.81
219.373.203.20