Basic Information
ID: ALA4052048
Type: ADME
Description: Inhibition of recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Nitric-oxide synthase, endothelial(ALA4803)
Document: ALA4049447
Inhibition of recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4052048
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.39 | 3.33 | 3.33 |
| 325.84 | 3.85 | 3.85 |
| 293.37 | 3.12 | 3.12 |
| 327.82 | 3.77 | 3.77 |
| 551.44 | 3.12 | 3.12 |
| 403.36 | 3.50 | 3.50 |
| 341.84 | 4.08 | 4.08 |
| 549.47 | 3.68 | 3.68 |
| 378.35 | 3.63 | 3.63 |
| 423.32 | 3.43 | 3.43 |
| 332.41 | 3.30 | 3.30 |
| 360.46 | 3.73 | 3.73 |
| 360.46 | 3.73 | 3.73 |
| 307.40 | 3.42 | 3.42 |
| 335.45 | 3.99 | 3.99 |
| 445.19 | 3.88 | 3.88 |
| 389.33 | 3.19 | 3.19 |
| 391.30 | 2.99 | 2.99 |
| 400.74 | 3.77 | 3.77 |
| 346.43 | 3.34 | 3.34 |
| 360.46 | 3.73 | 3.73 |