Basic Information
ID: ALA4052334
Type: Binding
Description: Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs followed by substrate addition measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4052334
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 70.09 | -0.14 | -0.14 |
| 423.82 | 4.60 | 4.60 |
| 367.81 | 1.49 | 1.49 |
| 399.83 | 3.28 | 3.28 |
| 236.70 | 2.33 | 2.33 |
| 138.17 | 0.55 | 0.55 |
| 359.43 | 3.53 | 3.53 |
| 212.60 | 1.56 | 1.56 |
| 369.85 | 3.26 | 3.26 |
| 493.94 | 5.50 | 5.50 |
| 417.82 | 2.56 | 2.56 |
| 206.29 | 2.25 | 2.25 |
| 337.81 | 1.71 | 1.71 |
| 435.81 | 2.51 | 2.51 |
| 394.40 | 3.63 | 3.63 |
| 443.82 | 1.77 | 1.77 |
| 454.86 | 1.37 | 1.37 |
| 448.35 | 2.55 | 2.55 |
| 337.81 | 1.71 | 1.71 |
| 373.82 | 3.72 | 3.72 |
| 394.40 | 3.63 | 3.63 |
| 355.83 | 3.58 | 3.58 |
| 360.34 | 5.14 | 5.14 |
| 367.81 | 1.49 | 1.49 |
| 425.94 | 4.48 | 4.48 |
| 355.83 | 3.58 | 3.58 |
| 453.29 | 2.52 | 2.52 |
| 421.80 | 1.43 | 1.43 |
| 385.85 | 3.59 | 3.59 |
| 377.75 | 2.64 | 2.64 |