Basic Information
ID: ALA4053420
Type: Binding
Description: Inhibition of LPS-induced NF-kappaB (unknown origin) transactivation expressed in human SW480 cells at 10 uM administered 1 hr after LPS stimulation measured after 6 hrs by luciferase reporter gene assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4053420
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.26 | 2.51 | 2.51 |
| 475.63 | 3.59 | 3.59 |
| 256.26 | 2.70 | 2.70 |
| 338.40 | 4.47 | 4.47 |
| 324.38 | 4.21 | 4.21 |
| 268.27 | 3.17 | 3.17 |
| 308.33 | 4.70 | 4.70 |
| 308.33 | 4.70 | 4.70 |
| 336.34 | 4.06 | 4.06 |
| 324.38 | 4.21 | 4.21 |
| 256.26 | 2.80 | 2.80 |
| 352.34 | 3.76 | 3.76 |
| 322.36 | 4.19 | 4.19 |
| 322.36 | 4.28 | 4.28 |
| 324.38 | 4.00 | 4.00 |
| 392.50 | 5.82 | 5.82 |
| 322.36 | 4.22 | 4.22 |
| 338.40 | 4.30 | 4.30 |
| 392.50 | 5.51 | 5.51 |
| 390.48 | 5.48 | 5.48 |
| 322.36 | 4.18 | 4.18 |
| 324.38 | 4.31 | 4.31 |
| 394.51 | 5.54 | 5.54 |
| 336.34 | 4.06 | 4.06 |
| 322.36 | 4.19 | 4.19 |
| 390.48 | 5.79 | 5.79 |
| 336.34 | 4.06 | 4.06 |
| 392.50 | 5.72 | 5.72 |
| 406.48 | 5.39 | 5.39 |
| 338.40 | 4.52 | 4.52 |
| 410.51 | 4.61 | 4.61 |
| 388.46 | 5.76 | 5.76 |
| 390.48 | 5.79 | 5.79 |
| 338.36 | 4.09 | 4.09 |
| 390.48 | 5.69 | 5.69 |
| 336.34 | 4.06 | 4.06 |
| 352.34 | 4.18 | 4.18 |
| 408.49 | 4.79 | 4.79 |
| 336.34 | 4.06 | 4.06 |
| 392.50 | 5.51 | 5.51 |
| 354.40 | 3.97 | 3.97 |
| 406.48 | 4.76 | 4.76 |
| 308.33 | 4.70 | 4.70 |
| 342.39 | 3.10 | 3.10 |
| 320.34 | 4.88 | 4.88 |
| 340.38 | 3.07 | 3.07 |
| 390.48 | 5.72 | 5.72 |
| 410.51 | 4.61 | 4.61 |
| 354.40 | 4.01 | 4.01 |
| 354.36 | 3.35 | 3.35 |
| 388.46 | 5.69 | 5.69 |
| 354.36 | 3.79 | 3.79 |
| 336.34 | 4.51 | 4.51 |
| 356.42 | 4.04 | 4.04 |
| 370.40 | 3.08 | 3.08 |
| 322.36 | 4.22 | 4.22 |
| 326.39 | 3.64 | 3.64 |