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Assay Report Card

Basic Information

ID: ALA4053621

Type: Binding

Description: Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins followed by PGH2 addition measured after 1 min by RP-HPLC analysis

Organism: Homo sapiens

Cell type: A549

Activity Charts

Bioactivity

Activity Types for Assay ALA4053621

IC50

Total(16)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
236.302.732.73
472.098.018.01
554.686.826.82
236.272.512.51
304.394.244.24
570.685.685.68
570.685.685.68
536.626.466.46
570.685.795.79
570.685.685.68
570.685.685.68
676.899.979.97
404.423.503.50
536.625.855.85
552.666.796.79
540.656.526.52
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