Assay Report Card

Basic Information

ID: ALA4053628

Type: Binding

Description: Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 assessed as residual activity at 10 uM using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by RP-HPLC analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
554.686.826.82
304.394.244.24
570.685.685.68
570.685.685.68
536.626.466.46
570.685.795.79
570.685.685.68
570.685.685.68
676.899.979.97
404.423.503.50
536.625.855.85
552.666.796.79
540.656.526.52