Basic Information
ID: ALA4053808
Type: Functional
Description: Selectivity ratio of IC50 for human NCI-H1975 cells harboring EGFR L858R/T790M double mutant to IC50 for human A431 cells harboring wild-type EGFR
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4052618
Selectivity ratio of IC50 for human NCI-H1975 cells harboring EGFR L858R/T790M double mutant to IC50 for human A431 cells harboring wild-type EGFR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4053808
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 555.68 | 4.93 | 4.93 |
| 537.67 | 4.92 | 4.92 |
| 529.65 | 4.52 | 4.52 |
| 499.62 | 4.51 | 4.51 |
| 529.65 | 4.52 | 4.52 |
| 525.66 | 4.92 | 4.92 |
| 523.64 | 4.67 | 4.67 |
| 551.70 | 5.31 | 5.31 |
| 525.66 | 4.92 | 4.92 |