Basic Information
ID: ALA4053813
Type: Binding
Description: Selectivity ratio of IC50 for human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) to IC50 for human recombinant cytoplasmic GST-tagged EGFR T790M/L858R double mutant (668 to 1210 residues)
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4052618
Selectivity ratio of IC50 for human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) to IC50 for human recombinant cytoplasmic GST-tagged EGFR T790M/L858R double mutant (668 to 1210 residues): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4053813
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 513.65 | 4.82 | 4.82 |
| 499.62 | 4.60 | 4.60 |
| 553.67 | 4.84 | 4.84 |
| 555.68 | 4.93 | 4.93 |
| 537.67 | 4.92 | 4.92 |
| 551.70 | 5.31 | 5.31 |
| 529.65 | 4.52 | 4.52 |
| 499.62 | 4.51 | 4.51 |
| 529.65 | 4.52 | 4.52 |
| 498.59 | 4.35 | 4.35 |
| 539.64 | 4.45 | 4.45 |
| 529.65 | 4.52 | 4.52 |
| 525.66 | 4.92 | 4.92 |
| 523.64 | 4.67 | 4.67 |
| 551.70 | 5.31 | 5.31 |
| 517.61 | 4.65 | 4.65 |
| 523.64 | 4.67 | 4.67 |
| 525.66 | 4.92 | 4.92 |