Basic Information
ID: ALA4053981
Type: Binding
Description: Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit in human U266 cells assessed as residual activity using N-Suc-LLVY-AMC as substrate at 10 uM preincubated for 1 hr followed by substrate addition and measured after 4 hrs by fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4053981
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.25 | ||
| 620.19 | 5.52 | 5.52 |
| 416.91 | 3.12 | 3.12 |
| 620.19 | 5.52 | 5.52 |
| 564.08 | 3.84 | 3.84 |
| 359.85 | 4.26 | 4.26 |
| 586.17 | 5.32 | 5.32 |
| 541.05 | 5.19 | 5.19 |
| 586.17 | 5.32 | 5.32 |
| 530.07 | 3.65 | 3.65 |
| 620.19 | 5.52 | 5.52 |
| 507.03 | 4.99 | 4.99 |
| 586.17 | 5.32 | 5.32 |
| 654.21 | 5.72 | 5.72 |
| 473.01 | 4.79 | 4.79 |
| 620.19 | 5.52 | 5.52 |
| 507.03 | 4.99 | 4.99 |
| 654.21 | 5.72 | 5.72 |
| 393.87 | 4.46 | 4.46 |