Basic Information
ID: ALA4054005
Type: Binding
Description: Inhibition of Klebsiella pneumoniae 6His-tagged NDM1 (G36 to R280 residues) expressed in Escherichia coli BL21 Star(DE3) pLysS using imipenem as substrate preincubated for 5 mins followed by substrate addition by spectrophotometric analysis
Organism: Klebsiella pneumoniae
Activity Charts
Bioactivity
Activity Types for Assay ALA4054005
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 238.35 | 3.03 | 3.03 |
| 274.32 | 2.88 | 2.88 |
| 302.33 | 2.84 | 2.84 |
| 262.34 | 1.81 | 1.81 |
| 316.40 | 4.57 | 4.57 |
| 244.23 | 1.55 | 1.55 |
| 314.36 | 4.03 | 4.03 |
| 258.25 | 1.94 | 1.94 |
| 330.50 | 4.37 | 4.37 |
| 260.30 | 2.49 | 2.49 |
| 330.43 | 4.96 | 4.96 |
| 290.39 | 2.59 | 2.59 |
| 302.38 | 4.18 | 4.18 |
| 230.20 | 1.16 | 1.16 |
| 316.36 | 3.23 | 3.23 |
| 300.33 | 3.64 | 3.64 |
| 248.36 | 2.24 | 2.24 |
| 246.27 | 2.10 | 2.10 |
| 288.31 | 2.45 | 2.45 |
| 286.31 | 3.25 | 3.25 |