Basic Information
ID: ALA4054008
Type: Binding
Description: Inhibition of Klebsiella pneumoniae NDM1 expressed in Escherichia coli SNO3 whole cells using imipenem as substrate at 250 uM preincubated for 20 mins followed by substrate addition measured every min up to 60 mins by spectrophotometric analysis relative to control
Organism: Klebsiella pneumoniae
Activity Charts
Bioactivity
Activity Types for Assay ALA4054008
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.32 | 2.88 | 2.88 |
| 302.33 | 2.84 | 2.84 |
| 262.34 | 1.81 | 1.81 |
| 316.40 | 4.57 | 4.57 |
| 314.36 | 4.03 | 4.03 |
| 258.25 | 1.94 | 1.94 |
| 330.50 | 4.37 | 4.37 |
| 344.41 | 4.53 | 4.53 |
| 260.30 | 2.49 | 2.49 |
| 372.47 | 5.31 | 5.31 |
| 330.43 | 4.96 | 4.96 |
| 290.39 | 2.59 | 2.59 |
| 302.38 | 4.18 | 4.18 |
| 230.20 | 1.16 | 1.16 |
| 316.36 | 3.23 | 3.23 |
| 300.33 | 3.64 | 3.64 |
| 358.44 | 4.92 | 4.92 |
| 248.36 | 2.24 | 2.24 |
| 246.27 | 2.10 | 2.10 |
| 288.31 | 2.45 | 2.45 |