Basic Information
ID: ALA4054227
Type: Binding
Description: Inhibition of full-length mouse 11beta-HSD1 expressed in HEK293 microsomal fraction at 1 uM using [3H]cortisone as substrate after 1 hr by scintillation proximity assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4054227
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 392.58 | 3.71 | 3.71 |
| 434.62 | 4.89 | 4.89 |
| 420.59 | 4.50 | 4.50 |
| 434.62 | 4.88 | 4.88 |
| 364.57 | 4.00 | 4.00 |
| 476.65 | 5.45 | 5.45 |
| 432.60 | 5.10 | 5.10 |
| 446.72 | 6.40 | 6.40 |
| 334.54 | 4.78 | 4.78 |
| 530.79 | 7.54 | 7.54 |
| 390.56 | 4.53 | 4.53 |
| 368.99 | 4.99 | 4.99 |
| 464.69 | 5.85 | 5.85 |
| 392.58 | 4.18 | 4.18 |
| 376.58 | 4.59 | 4.59 |
| 378.55 | 4.09 | 4.09 |
| 348.53 | 3.91 | 3.91 |
| 368.56 | 3.11 | 3.11 |
| 418.62 | 5.16 | 5.16 |
| 332.53 | 4.70 | 4.70 |
| 350.54 | 3.75 | 3.75 |
| 453.06 | 6.14 | 6.14 |
| 346.56 | 5.04 | 5.04 |
| 388.59 | 5.67 | 5.67 |
| 476.65 | 4.71 | 4.71 |
| 350.54 | 3.75 | 3.75 |
| 460.66 | 5.73 | 5.73 |
| 332.53 | 4.55 | 4.55 |
| 416.60 | 5.84 | 5.84 |
| 478.65 | 5.68 | 5.68 |
| 382.54 | 3.20 | 3.20 |
| 334.54 | 4.78 | 4.78 |
| 392.58 | 4.32 | 4.32 |
| 330.51 | 4.91 | 4.91 |
| 392.58 | 3.56 | 3.56 |