Assay Report Card

Basic Information

ID: ALA4054228

Type: Binding

Description: Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction at 1 uM using [3H]cortisone as substrate after 2 hr by scintillation proximity assay relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.696.416.41
392.583.713.71
434.624.894.89
420.594.504.50
434.624.884.88
364.574.004.00
476.655.455.45
432.605.105.10
446.726.406.40
334.544.784.78
530.797.547.54
390.564.534.53
368.994.994.99
464.695.855.85
392.584.184.18
376.584.594.59
378.554.094.09
348.533.913.91
368.563.113.11
418.625.165.16
332.534.704.70
350.543.753.75
453.066.146.14
346.565.045.04
388.595.675.67
476.654.714.71
350.543.753.75
460.665.735.73
332.534.554.55
416.605.845.84
478.655.685.68
382.543.203.20
334.544.784.78
392.584.324.32
330.514.914.91
392.583.563.56