Basic Information
ID: ALA4054229
Type: Binding
Description: Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation proximity assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4054229
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 434.62 | 4.88 | 4.88 |
| 530.79 | 7.54 | 7.54 |
| 476.65 | 4.71 | 4.71 |
| 460.66 | 5.73 | 5.73 |
| 392.58 | 4.32 | 4.32 |
| 330.51 | 4.91 | 4.91 |