Basic Information
ID: ALA4054735
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 15 mins by LC-MS/MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA4052642
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 15 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4054735
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.80 | 3.49 | 3.49 |
| 422.80 | 3.49 | 3.49 |
| 440.79 | 3.63 | 3.63 |
| 439.80 | 4.23 | 4.23 |
| 436.83 | 3.80 | 3.80 |