Basic Information
ID: ALA4054758
Type: Binding
Description: Antagonist activity at recombinant rat P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 mins followed by BzATP addition measured over 180 secs by FLIPR assay
Format: BAO_0000219
Organism: Rattus norvegicus
Target: P2X purinoceptor 7(ALA2496)
Document: ALA4052642
Antagonist activity at recombinant rat P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 mins followed by BzATP addition measured over 180 secs by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4054758
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.80 | 3.49 | 3.49 |
| 422.80 | 3.49 | 3.49 |
| 440.79 | 3.63 | 3.63 |
| 439.80 | 4.23 | 4.23 |
| 436.83 | 3.80 | 3.80 |