Basic Information
ID: ALA4054759
Type: Binding
Description: Antagonist activity at recombinant human P2X7 expressed in human 1321N1 cells assessed as inhibition of BzATP-induced calcium flux preincubated for 30 mins followed by BzATP addition measured over 180 secs by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4054759
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.80 | 3.49 | 3.49 |
| 422.80 | 3.49 | 3.49 |
| 440.79 | 3.63 | 3.63 |
| 439.80 | 4.23 | 4.23 |
| 436.83 | 3.80 | 3.80 |