Basic Information
ID: ALA4054824
Type: Binding
Description: Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISA
Format: BAO_0000223
Organism: Homo sapiens
Target: JAK3/JAK1(ALA3038491)
Document: ALA4052645
Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2 induced IFN-gamma production after 18 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4054824
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.48 | 2.81 | 2.81 |
| 392.51 | 3.12 | 3.12 |
| 392.51 | 3.12 | 3.12 |
| 391.52 | 3.73 | 3.73 |
| 367.46 | 2.14 | 2.14 |
| 411.94 | 4.07 | 4.07 |
| 378.48 | 2.81 | 2.81 |
| 391.52 | 3.73 | 3.73 |
| 408.51 | 2.82 | 2.82 |
| 436.56 | 3.60 | 3.60 |
| 402.50 | 3.29 | 3.29 |
| 407.52 | 3.43 | 3.43 |
| 395.48 | 3.56 | 3.56 |
| 392.51 | 3.12 | 3.12 |
| 395.48 | 3.56 | 3.56 |
| 407.52 | 3.43 | 3.43 |
| 411.94 | 4.07 | 4.07 |
| 395.48 | 3.56 | 3.56 |
| 407.52 | 3.43 | 3.43 |
| 396.47 | 2.95 | 2.95 |
| 408.51 | 2.82 | 2.82 |
| 402.50 | 3.29 | 3.29 |
| 392.51 | 3.12 | 3.12 |
| 391.52 | 3.73 | 3.73 |
| 396.47 | 2.95 | 2.95 |
| 379.47 | 2.21 | 2.21 |
| 422.53 | 3.21 | 3.21 |
| 402.50 | 3.29 | 3.29 |
| 377.49 | 3.42 | 3.42 |
| 403.49 | 2.68 | 2.68 |
| 396.47 | 2.95 | 2.95 |
| 396.47 | 2.95 | 2.95 |
| 411.94 | 4.07 | 4.07 |