Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver micro...

Basic Information

ID: ALA4055361

Type: Binding

Description: Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target: Acyl-CoA desaturase(ALA5555)

Document: ALA4052653

Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4055361

IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
367.41	2.16	2.16
489.45	4.61	4.61
488.44	4.74	4.74
418.50	3.38	3.38
353.38	1.51	1.51
396.84	2.73	2.73
396.84	2.73	2.73
362.39	2.08	2.08
405.38	3.12	3.12
473.38	4.14	4.14
446.39	2.98	2.98
352.40	1.47	1.47
489.45	4.61	4.61
430.39	3.10	3.10
407.39	1.99	1.99
396.84	2.73	2.73
473.38	4.14	4.14