Basic Information
ID: ALA4055638
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 5 uM using midazolam as substrate after 20 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4055638
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.47 | 2.11 | 2.11 |
| 428.36 | 1.02 | 1.02 |
| 567.91 | 2.74 | 2.74 |
| 491.50 | 0.90 | 0.90 |
| 428.36 | 1.02 | 1.02 |
| 533.46 | 2.09 | 2.09 |
| 412.37 | 2.05 | 2.05 |
| 533.58 | 1.66 | 1.66 |
| 505.53 | 1.02 | 1.02 |
| 456.37 | 1.36 | 1.36 |
| 484.43 | 2.14 | 2.14 |