Assay Report Card

Basic Information

ID: ALA4055639

Type: ADME

Description: Inhibition of CYP2C19 in human liver microsomes assessed as residual activity at 5 uM using S-mephenytoin as substrate after 20 mins by LC-MS/MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
429.472.112.11
428.361.021.02
567.912.742.74
491.500.900.90
428.361.021.02
533.462.092.09
412.372.052.05
533.581.661.66
505.531.021.02
456.371.361.36
484.432.142.14