Basic Information
ID: ALA4055845
Type: Binding
Description: Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after 1 hr by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: Poly [ADP-ribose] polymerase-1(ALA3105)
Document: ALA4052674
Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after 1 hr by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4055845
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 465.51 | 2.33 | 2.33 |
| 437.48 | 1.94 | 1.94 |
| 512.87 | 1.94 | 1.94 |
| 451.50 | 2.33 | 2.33 |
| 499.96 | 2.98 | 2.98 |
| 451.46 | 1.47 | 1.47 |
| 409.40 | 1.19 | 1.19 |
| 480.52 | 2.64 | 2.64 |
| 498.97 | 3.59 | 3.59 |
| 474.50 | 2.13 | 2.13 |
| 497.41 | 0.82 | 0.82 |
| 479.43 | 2.49 | 2.49 |
| 479.42 | 0.68 | 0.68 |
| 543.42 | 3.70 | 3.70 |
| 544.41 | 3.09 | 3.09 |
| 557.32 | 2.05 | 2.05 |
| 483.50 | 2.47 | 2.47 |
| 473.51 | 2.73 | 2.73 |
| 501.51 | 3.11 | 3.11 |
| 479.54 | 2.52 | 2.52 |
| 465.41 | 2.09 | 2.09 |
| 459.48 | 2.74 | 2.74 |
| 513.86 | 1.33 | 1.33 |
| 558.31 | 1.44 | 1.44 |
| 509.52 | 2.84 | 2.84 |