Assay Report Card

Basic Information

ID: ALA4055901

Type: Binding

Description: Inhibition of LRS-dependent mTORC1 activation in HEK293 cells assessed as reduction in leucine-induced mTORC1-mediated S6 Kinase phosphorylation at 200 uM pretreated before leucine stimulation measured after 10 mins by immunoblot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
375.492.482.48
452.531.501.50
435.552.492.49
376.482.512.51
436.532.532.53
392.481.481.48
586.37-1.58-1.58