Assay Report Card

Basic Information

ID: ALA4055916

Type: ADME

Description: Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as substrate at 10 uM by fluorescence spectrophotometric analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
354.392.402.40
500.463.933.93
438.513.293.29
438.513.293.29
348.362.342.34
438.512.902.90
398.423.493.49
460.523.033.03