Basic Information
ID: ALA4055916
Type: ADME
Description: Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as substrate at 10 uM by fluorescence spectrophotometric analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Matrix metalloproteinase 8(ALA4588)
Document: ALA4052682
Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as substrate at 10 uM by fluorescence spectrophotometric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4055916
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.39 | 2.40 | 2.40 |
| 500.46 | 3.93 | 3.93 |
| 438.51 | 3.29 | 3.29 |
| 438.51 | 3.29 | 3.29 |
| 348.36 | 2.34 | 2.34 |
| 438.51 | 2.90 | 2.90 |
| 398.42 | 3.49 | 3.49 |
| 460.52 | 3.03 | 3.03 |