Basic Information
ID: ALA4056329
Type: Binding
Description: Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after 48 hrs by MTT assay (Rvb = 43.75 to 96.91 uM)
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4052700
Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after 48 hrs by MTT assay (Rvb = 43.75 to 96.91 uM): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4056329
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 646.74 | 6.37 | 6.37 |
| 579.99 | 0.00 | 0.00 |
| 569.71 | 5.48 | 5.48 |
| 558.60 | 4.09 | 4.09 |
| 569.71 | 5.53 | 5.53 |
| 573.65 | 4.20 | 4.20 |
| 543.62 | 4.19 | 4.19 |
| 548.04 | 4.84 | 4.84 |
| 527.63 | 4.49 | 4.49 |
| 527.63 | 4.49 | 4.49 |
| 597.59 | 5.08 | 5.08 |
| 558.60 | 4.09 | 4.09 |
| 513.60 | 4.18 | 4.18 |
| 558.60 | 4.09 | 4.09 |
| 548.04 | 4.84 | 4.84 |
| 569.71 | 5.48 | 5.48 |
| 527.63 | 4.49 | 4.49 |
| 543.62 | 4.19 | 4.19 |
| 603.68 | 4.21 | 4.21 |
| 531.59 | 4.32 | 4.32 |