Basic Information
ID: ALA4056593
Type: ADME
Description: Inhibition of CYP3A4 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS method
Format: BAO_0000019
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4052712
Inhibition of CYP3A4 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4056593
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.28 | 0.74 | 0.74 |
| 700.79 | 4.57 | 4.57 |
| 527.40 | 4.63 | 4.63 |
| 521.40 | 4.44 | 4.44 |
| 533.43 | 4.07 | 4.07 |
| 577.51 | 5.14 | 5.14 |
| 623.56 | 5.81 | 5.81 |
| 584.53 | 4.88 | 4.88 |
| 471.39 | 3.57 | 3.57 |
| 616.58 | 4.36 | 4.36 |
| 487.84 | 4.08 | 4.08 |
| 602.52 | 5.02 | 5.02 |
| 584.53 | 4.88 | 4.88 |
| 584.53 | 4.88 | 4.88 |
| 643.52 | 5.90 | 5.90 |
| 600.99 | 5.39 | 5.39 |
| 584.53 | 4.88 | 4.88 |
| 487.84 | 4.08 | 4.08 |
| 550.44 | 4.40 | 4.40 |
| 627.52 | 6.02 | 6.02 |
| 471.39 | 3.57 | 3.57 |
| 602.52 | 5.02 | 5.02 |