Assay Report Card

Basic Information

ID: ALA4056671

Type: Binding

Description: Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as substrate preincubated for 20 mins in presence of [3H]SAM measured after 2 hrs by scintillation proximity assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
373.503.003.00
345.452.222.22
387.533.393.39
387.533.253.25
386.502.592.59
427.594.174.17
375.471.581.58
373.503.003.00
389.501.971.97
415.542.772.77
385.513.143.14
402.542.152.15
375.472.212.21
417.553.123.12
389.502.242.24
399.543.903.90
373.503.003.00
400.574.754.75
421.553.793.79
407.523.923.92
359.472.612.61
387.533.613.61
399.543.533.53
401.563.643.64
413.573.923.92
415.584.174.17
371.492.752.75
415.584.394.39
401.563.783.78