Basic Information
ID: ALA4056822
Type: Binding
Description: Inhibition of recombinant human neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Neprilysin(ALA1944)
Document: ALA4052733
Inhibition of recombinant human neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4056822
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.42 | 2.34 | 2.34 |
| 517.45 | 4.18 | 4.18 |
| 407.33 | 4.19 | 4.19 |
| 478.41 | 3.70 | 3.70 |
| 373.31 | 4.00 | 4.00 |
| 368.50 | 4.80 | 4.80 |
| 345.26 | 3.36 | 3.36 |
| 490.42 | 4.26 | 4.26 |
| 382.53 | 5.19 | 5.19 |
| 382.53 | 5.19 | 5.19 |
| 416.54 | 5.02 | 5.02 |
| 593.54 | 5.40 | 5.40 |
| 399.51 | 3.38 | 3.38 |
| 388.55 | 5.25 | 5.25 |
| 464.38 | 3.83 | 3.83 |
| 399.51 | 2.93 | 2.93 |
| 520.49 | 4.72 | 4.72 |
| 441.59 | 4.41 | 4.41 |
| 386.31 | 2.70 | 2.70 |
| 388.55 | 5.25 | 5.25 |
| 483.43 | 5.86 | 5.86 |
| 514.65 | 4.64 | 4.64 |
| 407.33 | 4.19 | 4.19 |
| 475.61 | 4.60 | 4.60 |
| 373.31 | 4.14 | 4.14 |
| 371.30 | 3.89 | 3.89 |
| 444.39 | 3.50 | 3.50 |
| 382.53 | 5.19 | 5.19 |
| 442.42 | 3.77 | 3.77 |
| 419.34 | 4.12 | 4.12 |
| 428.35 | 2.96 | 2.96 |
| 383.51 | 3.61 | 3.61 |
| 385.32 | 4.28 | 4.28 |
| 388.55 | 5.25 | 5.25 |
| 328.43 | 3.43 | 3.43 |
| 486.23 | 4.96 | 4.96 |
| 476.44 | 4.62 | 4.62 |