Basic Information
ID: ALA4057011
Type: Functional
Description: Reduction in intraocular pressure in Chinchilla rabbit assessed as maximum effective time required for reduction of intraaocular pressure at 0.1% after application of one drop (0.06 ml) of solution containing active compound/vehicle every hour (during 6 hours and after 24 hours) and measured after 24 hrs post dose by automatic tonometry
Organism: Oryctolagus cuniculus
Strain: Chinchilla
Activity Charts
Bioactivity
Activity Types for Assay ALA4057011
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 232.28 | 1.86 | 1.86 |
| 316.43 | 0.50 | 0.50 |
| 246.31 | 1.87 | 1.87 |
| 266.73 | 2.51 | 2.51 |
| 229.24 | 1.59 | 1.59 |
| 275.31 | 1.21 | 1.21 |
| 243.27 | 1.62 | 1.62 |
| 291.31 | 0.31 | 0.31 |
| 293.27 | 0.99 | 0.99 |
| 251.08 | 2.40 | 2.40 |
| 314.39 | 2.07 | 2.07 |
| 274.32 | 1.07 | 1.07 |
| 264.24 | 0.26 | 0.26 |
| 229.24 | 1.59 | 1.59 |
| 245.24 | 0.70 | 0.70 |
| 330.34 | 1.44 | 1.44 |
| 317.30 | 1.28 | 1.28 |
| 244.34 | 2.47 | 2.47 |
| 297.15 | 2.01 | 2.01 |
| 386.41 | 2.40 | 2.40 |
| 344.33 | 1.23 | 1.23 |
| 202.21 | 1.64 | 1.64 |