Basic Information
ID: ALA4057740
Type: ADME
Description: Inhibition of human CYP3A4 bound to yeast microsomal membrane using dibenzylfluorescein as substrate after 10 mins by fluorescence assay
Format: BAO_0000019
Organism: Homo sapiens
Subcellular Fraction: Microsomal Membrane
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4052762
Inhibition of human CYP3A4 bound to yeast microsomal membrane using dibenzylfluorescein as substrate after 10 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4057740
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.30 | 4.61 | 4.61 |
| 231.68 | 3.56 | 3.56 |
| 241.25 | 2.64 | 2.64 |
| 227.26 | 2.92 | 2.92 |
| 257.29 | 2.93 | 2.93 |
| 240.31 | 2.98 | 2.98 |
| 257.29 | 2.93 | 2.93 |
| 276.68 | 3.47 | 3.47 |
| 276.13 | 3.67 | 3.67 |
| 257.29 | 2.93 | 2.93 |
| 227.26 | 2.92 | 2.92 |
| 231.68 | 3.56 | 3.56 |
| 253.30 | 3.48 | 3.48 |
| 276.13 | 3.67 | 3.67 |
| 223.28 | 3.47 | 3.47 |
| 297.36 | 5.22 | 5.22 |
| 215.25 | 3.07 | 3.07 |
| 281.23 | 3.81 | 3.81 |
| 215.23 | 3.05 | 3.05 |
| 257.29 | 2.93 | 2.93 |
| 306.16 | 3.68 | 3.68 |
| 287.31 | 2.94 | 2.94 |
| 241.25 | 2.61 | 2.61 |
| 227.26 | 2.92 | 2.92 |