Inhibition of recombinant human CYP2D6 expressed in baculosomes assessed as residual activity at 10 uM using vivid EOMCC/MOBFC as substrate after 15 m...

Basic Information

ID: ALA4057906

Type: ADME

Description: Inhibition of recombinant human CYP2D6 expressed in baculosomes assessed as residual activity at 10 uM using vivid EOMCC/MOBFC as substrate after 15 mins in presence of NADPH by fluorescence assay relative to control

Format: BAO_0000019

Organism: Homo sapiens

Target:  Cytochrome P450 2D6(ALA289)

Document:  ALA4052773

Inhibition of recombinant human CYP2D6 expressed in baculosomes assessed as residual activity at 10 uM using vivid EOMCC/MOBFC as substrate after 15 mins in presence of NADPH by fluorescence assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
367.473.703.70
383.523.863.86
347.483.473.47
385.463.843.84