Inhibition of recombinant human CYP3A4 expressed in baculosomes assessed as residual activity at 10 uM using vivid BOMCC/DBOMF/BOMR as substrate after...

Basic Information

ID: ALA4057908

Type: ADME

Description: Inhibition of recombinant human CYP3A4 expressed in baculosomes assessed as residual activity at 10 uM using vivid BOMCC/DBOMF/BOMR as substrate after 15 mins in presence of NADPH by fluorescence assay relative to control

Format: BAO_0000019

Organism: Homo sapiens

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA4052773

Inhibition of recombinant human CYP3A4 expressed in baculosomes assessed as residual activity at 10 uM using vivid BOMCC/DBOMF/BOMR as substrate after 15 mins in presence of NADPH by fluorescence assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
367.473.703.70
383.523.863.86
347.483.473.47
385.463.843.84