Basic Information
ID: ALA4058262
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-FLAG-tagged BRD4 bromodomain 1 expressed in Rosetta2 (DE3) pLysS cells after 60 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4058262
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.50 | 3.16 | 3.16 |
| 330.43 | 1.81 | 1.81 |
| 448.57 | 3.34 | 3.34 |
| 458.53 | 2.23 | 2.23 |
| 460.46 | 3.07 | 3.07 |
| 498.59 | 3.72 | 3.72 |
| 486.55 | 3.85 | 3.85 |
| 422.49 | 2.06 | 2.06 |
| 420.52 | 2.66 | 2.66 |
| 458.52 | 3.31 | 3.31 |
| 392.46 | 2.05 | 2.05 |
| 498.59 | 3.72 | 3.72 |
| 432.57 | 4.12 | 4.12 |
| 432.57 | 4.12 | 4.12 |
| 436.52 | 2.36 | 2.36 |
| 446.56 | 3.23 | 3.23 |
| 302.38 | 1.03 | 1.03 |
| 418.54 | 3.81 | 3.81 |
| 432.53 | 2.92 | 2.92 |
| 288.35 | 0.69 | 0.69 |
| 482.59 | 4.02 | 4.02 |