Basic Information
ID: ALA4058411
Type: Binding
Description: Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracellular Ca2+ levels measured after 1 day post induction by Fluo-3/AM dye-based fluorescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4058411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.41 | 3.09 | 3.09 |
| 416.42 | 3.89 | 3.89 |
| 399.88 | 3.78 | 3.78 |
| 448.44 | 4.63 | 4.63 |
| 364.45 | 3.74 | 3.74 |
| 405.42 | 4.79 | 4.79 |
| 380.44 | 3.61 | 3.61 |
| 414.89 | 4.27 | 4.27 |
| 438.91 | 5.14 | 5.14 |
| 373.40 | 4.05 | 4.05 |
| 378.47 | 3.67 | 3.67 |
| 371.87 | 4.42 | 4.42 |
| 404.47 | 4.48 | 4.48 |
| 398.89 | 4.39 | 4.39 |
| 363.46 | 4.06 | 4.06 |
| 371.87 | 4.42 | 4.42 |
| 398.43 | 3.75 | 3.75 |
| 464.44 | 4.51 | 4.51 |
| 367.45 | 3.78 | 3.78 |
| 380.44 | 3.61 | 3.61 |
| 410.47 | 3.62 | 3.62 |
| 421.42 | 4.67 | 4.67 |
| 337.42 | 3.77 | 3.77 |
| 398.89 | 4.39 | 4.39 |
| 392.50 | 4.06 | 4.06 |
| 355.41 | 3.91 | 3.91 |
| 398.43 | 3.75 | 3.75 |