Assay Report Card

Basic Information

ID: ALA4058664

Type: Functional

Description: In vivo inhibition of CBP in human MOLM16 cells xenografted in C.B-17 SCID beige mouse assessed as suppression of MYC transcript levels at 3 mg/kg administered via oral gavage as bid for 21 days measured 2 to 8 hrs post last dose by real time-PCR method

Organism: Mus musculus

Strain: C.B-17

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
525.604.354.35