Basic Information
ID: ALA4058861
Type: Binding
Description: Allosteric modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aorta assessed as change in human urotensin-2-mediated aortic ring contraction by measuring urotensin-2 pEC50 at 10'-5M preincubated for 15 mins followed by urotensin-2 addition (Rvb = 8.61 +/- 0.05 No_unit)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4058861
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 570.16 | 6.97 | 6.97 |
| 539.08 | 6.27 | 6.27 |
| 610.23 | 7.74 | 7.74 |
| 529.08 | 5.98 | 5.98 |
| 529.08 | 6.06 | 6.06 |
| 582.17 | 7.09 | 7.09 |
| 555.12 | 6.49 | 6.49 |
| 556.14 | 6.58 | 6.58 |
| 567.13 | 6.96 | 6.96 |
| 527.07 | 6.14 | 6.14 |
| 556.14 | 6.58 | 6.58 |
| 596.20 | 7.48 | 7.48 |
| 570.16 | 6.97 | 6.97 |
| 515.06 | 5.67 | 5.67 |
| 553.11 | 6.57 | 6.57 |
| 513.04 | 5.75 | 5.75 |
| 543.11 | 6.37 | 6.37 |
| 584.19 | 7.23 | 7.23 |
| 555.12 | 6.58 | 6.58 |
| 596.20 | 7.35 | 7.35 |
| 541.10 | 6.45 | 6.45 |
| 541.10 | 6.19 | 6.19 |
| 584.19 | 7.23 | 7.23 |
| 527.07 | 6.06 | 6.06 |
| 553.11 | 6.66 | 6.66 |
| 569.15 | 6.88 | 6.88 |