Basic Information
ID: ALA4058875
Type: Binding
Description: Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in human urotensin-2-induced G12 activation by measuring urotensin-2 pEC50 at 10'-5 M preincubated for 30 mins followed by urotensin-2 addition by BRET assay (Rvb = 6.31 +/- 0.17 No_unit)
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4058875
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.08 | 6.06 | 6.06 |
| 567.13 | 6.96 | 6.96 |
| 556.14 | 6.58 | 6.58 |
| 553.11 | 6.66 | 6.66 |