Basic Information
ID: ALA4059290
Type: Binding
Description: Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4059290
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.39 | 3.64 | 3.64 |
| 357.45 | 3.49 | 3.49 |
| 193.25 | 1.39 | 1.39 |
| 207.27 | 1.69 | 1.69 |
| 349.21 | 1.84 | 1.84 |
| 191.23 | 1.40 | 1.40 |
| 233.31 | 2.40 | 2.40 |
| 217.27 | 2.11 | 2.11 |
| 377.27 | 2.62 | 2.62 |
| 283.37 | 3.26 | 3.26 |
| 283.37 | 3.26 | 3.26 |
| 335.19 | 1.53 | 1.53 |
| 217.27 | 2.11 | 2.11 |
| 345.22 | 2.53 | 2.53 |
| 295.38 | 4.18 | 4.18 |
| 359.21 | 2.25 | 2.25 |
| 328.25 | 2.39 | 2.39 |
| 333.17 | 1.55 | 1.55 |
| 275.35 | 1.81 | 1.81 |
| 173.26 | 2.38 | 2.38 |
| 177.25 | 1.68 | 1.68 |
| 233.31 | 2.40 | 2.40 |
| 359.21 | 2.25 | 2.25 |
| 217.27 | 2.11 | 2.11 |
| 295.38 | 4.18 | 4.18 |
| 375.25 | 2.54 | 2.54 |
| 375.25 | 2.54 | 2.54 |
| 345.22 | 2.53 | 2.53 |
| 425.31 | 3.41 | 3.41 |
| 375.25 | 2.54 | 2.54 |
| 378.31 | 3.41 | 3.41 |
| 233.31 | 2.40 | 2.40 |
| 315.20 | 2.52 | 2.52 |
| 437.32 | 4.33 | 4.33 |
| 363.24 | 2.23 | 2.23 |
| 203.28 | 2.39 | 2.39 |
| 319.19 | 1.83 | 1.83 |
| 425.31 | 3.41 | 3.41 |
| 359.21 | 2.25 | 2.25 |
| 203.28 | 2.39 | 2.39 |
| 437.32 | 4.33 | 4.33 |