Basic Information
ID: ALA4059292
Type: Binding
Description: Antagonist activity at human alpha7 nAChR expressed in HEK293 cells co-expressing Ric-3/NACHO assessed as inhibition of ACh-induced calcium mobilization measured up to 90 secs in presence of PNU-120596 by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4059292
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.45 | 3.49 | 3.49 |
| 193.25 | 1.39 | 1.39 |
| 207.27 | 1.69 | 1.69 |
| 191.23 | 1.40 | 1.40 |
| 233.31 | 2.40 | 2.40 |
| 377.27 | 2.62 | 2.62 |
| 283.37 | 3.26 | 3.26 |
| 283.37 | 3.26 | 3.26 |
| 295.38 | 4.18 | 4.18 |
| 328.25 | 2.39 | 2.39 |
| 275.35 | 1.81 | 1.81 |
| 173.26 | 2.38 | 2.38 |
| 177.25 | 1.68 | 1.68 |
| 233.31 | 2.40 | 2.40 |
| 295.38 | 4.18 | 4.18 |
| 378.31 | 3.41 | 3.41 |
| 233.31 | 2.40 | 2.40 |
| 203.28 | 2.39 | 2.39 |