Basic Information
ID: ALA4118540
Type: Binding
Description: Inhibition of biotin-labeled N-(2-(2-(2-(2-(4-(4-((4-((2-Acrylamidophenyl)amino)-5-chloropyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide probe binding to TAK1 in human NCI-H358 cells at 10 uM after 6 hrs by immunoblot based competitive pull down assay
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA4118540
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.99 | 4.72 | 4.72 |
| 466.97 | 4.77 | 4.77 |
| 451.91 | 4.55 | 4.55 |
| 406.78 | 4.38 | 4.38 |
| 414.85 | 3.63 | 3.63 |
| 464.96 | 4.54 | 4.54 |
| 416.87 | 3.86 | 3.86 |
| 486.41 | 4.55 | 4.55 |