Basic Information
ID: ALA4119061
Type: Binding
Description: Inhibition of TAK1 in RA patient-derived synovial fibroblasts assessed as inhibition of TNFalpha-induced cytokine secretion at 3 uM preincubated for 3 hrs followed by TNFalpha stimulation measured after 18 hrs by sandwich immunoassay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4119061
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.97 | 4.77 | 4.77 |
| 414.85 | 3.63 | 3.63 |
| 464.96 | 4.54 | 4.54 |
| 537.59 | 6.07 | 6.07 |
| 416.87 | 3.86 | 3.86 |