Basic Information
ID: ALA4119285
Type: Functional
Description: Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLF/CB-induced elastase release by measuring degranulation of azurophilic granules using MeOSuc-Ala-Ala-ProVal-p-nitroanilide as substrate preincubated for 5 mins followed by CB/fMLF stimulation
Organism: Homo sapiens
Cell type: Neutrophil
Activity Charts
Bioactivity
Activity Types for Assay ALA4119285
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.35 | 3.30 | 3.30 |
| 514.57 | 1.36 | 1.36 |
| 654.93 | 8.12 | 8.12 |
| 621.00 | 11.51 | 11.51 |
| 502.69 | 4.65 | 4.65 |
| 474.64 | 3.87 | 3.87 |
| 594.96 | 10.95 | 10.95 |