Basic Information
ID: ALA4119626
Type: Functional
Description: Activity at alpha2 adrenergic receptor in human brain prefrontal cortex membranes assessed as effect on UK14304-induced [35S]GTPgammaS binding by measuring UK14304 EC50 at 10'-5 M after 120 mins by microbeta liquid scintillation spectrometry (Rvb = 0.4 +/- 0.01 uM)
Organism: Homo sapiens
Tissue: Prefrontal cortex
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4119626
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.75 | 1.93 | 1.93 |
| 232.74 | 1.33 | 1.33 |
| 245.78 | 2.32 | 2.32 |
| 256.76 | 1.80 | 1.80 |
| 217.72 | 1.54 | 1.54 |
| 218.71 | 0.94 | 0.94 |
| 205.71 | 0.77 | 0.77 |