Basic Information
ID: ALA4119868
Type: Binding
Description: Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Mitogen-activated protein kinase kinase kinase 12(ALA1908389)
Document: ALA4118097
Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4119868
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.51 | 3.89 | 3.89 |
| 415.41 | 4.04 | 4.04 |
| 433.48 | 4.60 | 4.60 |
| 399.93 | 4.24 | 4.24 |
| 383.47 | 3.72 | 3.72 |
| 409.46 | 3.71 | 3.71 |
| 375.90 | 3.34 | 3.34 |
| 393.41 | 3.32 | 3.32 |
| 409.46 | 3.42 | 3.42 |
| 407.44 | 3.17 | 3.17 |
| 405.45 | 2.75 | 2.75 |
| 369.47 | 2.16 | 2.16 |
| 419.45 | 3.00 | 3.00 |
| 389.45 | 3.09 | 3.09 |
| 433.48 | 3.39 | 3.39 |
| 423.44 | 3.05 | 3.05 |
| 447.38 | 3.15 | 3.15 |
| 435.45 | 2.88 | 2.88 |
| 421.47 | 3.42 | 3.42 |
| 379.39 | 2.13 | 2.13 |
| 437.47 | 2.36 | 2.36 |
| 395.39 | 2.01 | 2.01 |
| 447.51 | 3.78 | 3.78 |
| 421.47 | 3.25 | 3.25 |
| 409.46 | 3.15 | 3.15 |
| 393.41 | 2.61 | 2.61 |