Assay Report Card

Basic Information

ID: ALA4120993

Type: Binding

Description: Inhibition of Influenza A virus (A/NWS/G70C(H1N9)) neuraminidase activity using 4-MUNANA as substrate assessed as reactivation half life by measuring reaction rate to reach 50% of maximum rate of uninhibited control after removal of inhibitor preincubated for 30 mins followed by compound washout and subsequent substrate addition measured after each 10 mins for 4 hrs by fluorescence assay (Rvb = 10.9 +/- 2.1 min)

Organism: Influenza A virus (A/NWS/G70C(H1N9))

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
332.31-3.58-3.58
313.25-1.92-1.92
313.25-1.92-1.92
313.25-1.92-1.92
313.25-1.92-1.92
329.25-2.95-2.95